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KMID : 0367419940370040553
Journal of Korean Pediatric Society
1994 Volume.37 No. 4 p.553 ~ p.559
Furosemide-Induced Nephrocalcinosis in Very Low Birth Weight Infants
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Abstract
Renal calcifications are a recognized complication of furosemide therapy in premature infants. Particularly in infants with chronic lung disease, the use of this potent diuretic is associated with hypercalciuria, which may predispose the infant
to
medullary nephrocalcinosis and renal calculi, We experienced two cases of nephrocalcinosis in very low birth weight infants. One had bronchopulmonary dysplasia, pneumonia, patent ductus arteriosus, ventricular septal defect and congestive heart
failure
and the other had systemic cytomegalovirus infection with cytomegalovirus pneumonitis and ricket of prematurity. Both patients received a large amount of furosemide.
We presented these cases with brief review of literatures.
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